February 10, 2017 Send an email to ORIE@wustl.edu referencing the project number Indicate the reason for the closure. For example: No longer using hESCs Lost funding Project completed Leaving Washington University Describe your plans for the hESCs: Destruction Transfer to another Washington University investigator Take to new institution ESCRO will review the terms of the […]
Category: How-Tos
Determine if an MTA is Needed for Stem Cells
February 10, 2017 A Materials Transfer Agreement (MTA) is required for both incoming and outgoing materials. A MTA typically is required when human embryonic stem cells (hESC) are received or shared between Washington University investigators and other academic or industry partners. An MTA or approval/authorization also may be required to obtain hESCs from the WU […]
Submit Stem Cell Project Amendment
February 10, 2017 Complete the ESCRO Amendment (DOC) and email to ORIE@wustl.edu. ESCRO approval covers only the research and specific use of hESC/hPSC/hiPSC lines described in your approved ESCRO application. Any change in the research or hES cell lines approved by ESCRO must be submitted as an Amendment and approved by ESCRO before making the change. […]
Submit Stem Cell Project Annual Renewal
February 10, 2017 ESCRO approval is required annually. You will receive a reminder email approximately six weeks before your expiration date. To continue approval of your ESCRO project: Complete the Renewal Form (DOC) Have the form signed by your department chair Email all documents to ORIE@wustl.edu
Determine Who Can be a PI on an ESCRO Project
February 10, 2017 PIs are usually Washington University faculty members with appointments of instructor or above. However, postdocs who receive their own funding for research using hESC/hPSC (e.g., fellowship award, internal seed grant) will be the PI on the ESCRO application. The research must be overseen by a faculty member, usually the mentor on the […]
Submit New Stem Cell Project Application
February 10, 2017 Complete the ESCRO Application [DOC]. Attach research plan (required) For department funded research, attach a description of research significance and background, experimental design, and potential outcomes (see ESCRO Research Plan Template [DOC]). For sponsored research, attach awarded grant application(s) that supports this research. If proposing to generate new hESC lines or use hESCs […]
Determine if ESCRO Approval is Needed
February 10, 2017 ESCRO review and approval is needed when any of the following biological materials are used for research purposes: Human embryonic stem cells (hESC) Materials derived from a human embryo, including hESC-derived neural progenitors and other hESC derivatives Other human pluripotent stem cells, including human induced pluripotent stem cells (hiPSC) or their derivatives […]
Find Penalties for Violations
Civil Penalties EAR ITAR OFAC University Up to $120,000 per violation Up to $500,000 per violation Up to $55,000 per violation Individual (PI) Up to $120,000 per violation Up to $500,000 per violation Up to $55,000 per violaton Criminal Penalties EAR ITAR OFAC University Up to $1 million per violation Up to $1 million […]
Know Which Countries, Entities, and Persons are Restricted
Restricted Countries, Entities, and Persons The U.S. Department of the Treasury, through its Office of Foreign Assets Control (OFAC), enforces U.S. embargo and sanction programs that may restrict transactions with certain foreign countries irrespective of whether the exported technology is controlled under the ITAR or the EAR. Sanctions programs vary in severity. In cases where a country is […]
Know Which Types of Items are Controlled
“Dual-Use” Technologies The controlled technologies most commonly found on campus are “dual-use” technologies covered by the Export Administration Regulations (EAR). These are items or technologies with potential for both civilian and military use (the military use may not be obvious). Dual-use items can be found on the Commerce Control List (CCL). Each category on the CCL […]