Federal Agency Guidance

Last Update: August 18, 2025
This page will be updated as new information is made available.

CDC – Centers for Disease Control & Prevention

• DEI Restrictions (Domestic) – 1/29/2025 – Rescinded

CHCO – Chief Human Capital Officers Council

• Initial Guidance Regarding DEIA Executive Orders – 1/21/2025

DOD – Department of Defense

• Implementation of Secretary of Defense Indirect Cost Cap Memo – 6/12/2025
• Implementation of a 15% Indirect Cost Cap on Assistance Awards to Institutions of Higher Education – 5/14/2025
• Department of Defense Statement Clarifying Defense Contracting – 1/28/2025

DOE – Department of Energy

• Adjusting Department of Energy Grant Policy for Institutions of Higher Education (IHE) – 4/11/2025
  • Association of American Universities v. Department of Energy, Order Granting Plaintiffs’ Motion for a Temporary Restraining Order – 4/16/2025
• Suspension of DEI, CBP, PIER, and Justice40 – 1/31/2025
• Agency-wide Review of Program and Administrative Activities – 1/20/2025

DOJ – Department of Justice

• Guidance for Recipients of Federal Funding Regarding Unlawful Discrimination -Memo from the Attorney General – 7/29/2025

DHHS – Department of Health and Human Services

• Substance Abuse and Mental Health Services Administration (SAMHSA) Dear Colleague Letter – Executive Order on Ending Crime and Disorder on America’s Streets – 7/29/2025
• Payment Management System (PMS) Payment Delays Due to Executive Orders – 1/27/2025
  • Effective immediately, PMS is only available during the hours of 9 a.m. to 4 p.m. EST, Monday – Friday. The limited hours are in effect until a further notice.
  • PAYMENT DELAYS: Due to Executive Orders regarding potentially unallowable grant payments, PMS is taking additional measures to process payments. Reviews of applicable programs and payments will result in delays and/or rejections of payments.

FDA – Food and Drug Administration

• Recording: FDA & NIH Workshop on Reducing Animal Testing – 7/7/2025
• FDA Announces Plan to Phase Out Animal Testing Requirement for Monoclonal Antibodies and Other Drugs – 4/10/2025
  • Roadmap to Reducing Animal Testing in Preclinical Safety Studies

HRSA – Health Resources and Services Administration

• Dear Colleague Letter from HRSA Administrator Thomas J. Engels – 4/8/2025
• Letter to Hospital Administrators, Colleagues, and Grant Recipients from HRSA Administrator – 3/6/2025

NASA – National Aeronautics and Space Administration

• New Webform for RPPR Submission – Effective 8/13/2025 – 8/18/2025
• NASA Payment Request Monthly Cut-off Update – 4/1/2025
• [NASA Watch] Janet Petro NASA Update – 2/21/2025
• Amendment 109: Removing DEIA Requirements from ROSES-2024

NEA – National Endowment for the Arts

• Assurance of Compliance (updated March 2025)
  • By signing and submitting its application form on Grants.gov, the applicant certifies that it is in compliance with the statutes outlined below and all related National Endowment for the Arts regulations as well as all applicable executive orders, and that it will maintain records and submit the reports that are necessary to determine its compliance.
    • In addition, the applicant agrees that, if the applicant is selected and becomes a NEA grant recipient:  The applicant will comply with all applicable Executive Orders while the award is being administered. 
• NEA Notice – 4/30/2025
• Grants Management Policy and Guidance for Awards to Organizations – 4/2/2025

NEH – National Endowment for the Humanities

• Compliance with Executive Orders (Updated March 2025)
  • The recipient, including any subrecipient(s), must comply with all applicable Executive Orders for the duration of the period of performance of the award. Executive Orders can be accessed via the Federal Register :: Executive Orders, and additional guidance is provided on NEH’s website.
  • Impacts to funded projects:  NEH has cancelled awards that are at variance with agency priorities, including but not limited to those on diversity, equity, and inclusion (or DEI) and environmental justice, as well as awards that may not inspire public confidence in the use of taxpayer funds.
• An Update on NEH Funding Priorities and the Agency’s Recent Implementation of Trump Administration Executive Orders – 4/24/2025
• NEH Implementation of Recent Executive Orders – 3/20/2025

NIH – National Institutes of Health

• NIH Will Stop Posting Notices of Funding Opportunities in the NIH Guide for Grants and Contracts in FY2026 [NOT-OD-25-143] – 8/14/2025
• Update: No-Cost Extension Functionality in eRA [NOT-OD-25-142] – 8/7/2025
• Reminder: Unauthorized Use of Credentials is Prohibited [NOT-OD-25-139] – 7/30/2025
• Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs [NOT-OD-25-138] – 7/30/2025
• NIH Intramural Research Program Access Planning Policy Implementation Guidance [NOT-OD-25-137] – 7/24/2025
• NIH Intramural Research Program Access Planning Policy [NOT-OD-25-136] – 7/24/2025
• Notice to Applicants of Adjustments to Achieve Consistency in Peer Review Contacts and Processes [NOT-OD-25-135] – 7/24/2025
• National Cancer Institute (NCI) Full Year Funding Policy for RPG Awards FY 2025 – updated 7/23/2025
• Updated Implementation Guidance of NIH Policy on Foreign Subawards for Active Projects [NOT-OD-25-130] – 7/18/2025
  • NIH Frequently Asked Questions on Foreign Subaward Policy
• NIH Announces a New Policy Requirement to Train Senior/Key Personnel on Other Support Disclosure Requirements [NOT-OD-25-133] – 7/17/2025
• Supporting Fairness and Originality in NIH Research Applications [NOT-OD-25-132] – 7/17/2025
  • NIH FAQs – Use of Generative AI in Peer Review
• NIH Funding Announcements to Align with NIH Initiative to Prioritize Human-based Research – 7/10/2025
• NIH to crack down on excessive publisher fees for publicly funded research – 7/8/2025
• Guidance on Enforcement of Closeout Requirements During the Appeals Process [NOT-OD-25-128] – 7/7/2025
• Recording: FDA & NIH Workshop on Reducing Animal Testing – 7/7/2025
• RESCINDED: Notice of Civil Rights Term and Condition of Award [NOT-OD-20-178]
  • Rescinded 6/9/2025 [NOT-OD-25-124]*
    • As of 6/10/2025, this NOT could not be found on NIH’s website.
    • The NOT was re-issued on 6/11/2025.
• Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibility for Mentored Career Development Award When an Award Ended Early [NOT-OD-25-115] – 5/28/2025
• Implementation Update: Improving the Safety and Security of Biological Research [NOT-OD-25-112] – 5/7/2025
• Updated NIH Processes for No-Cost Extensions [NOT-OD-25-110] – 5/7/2025
  • NCE Request Guidance for NIH
• Updated NIH Policy on Foreign Subawards [NOT-OD-25-104] – 5/1/2025
  • Summary of Updated NIH Policy on Foreign Subawards – Updated 5/14/2025
• Accelerating Access to Research Results: New Implementation Date for the 2024 NIH Public Access Policy – 4/30/2025
• Updated Procedures for Childcare Costs for Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Awards [NOT-OD-25-100] – 4/25/2025
• Reminder: Application Requirements for Projects Involving Activities Outside of the United States or Partnerships with International Collaborators [NOT-OD-25-098] – 4/23/2025
• Notice of Civil Rights Term and Condition of Award [NOT-OD-25-090] – 4/21/2025
• Implementation Update: Enhancing Security Measures for NIH Controlled-Access Data [NOT-OD-25-083] – 4/2/2025
• Protecting Human Genomic Data when Developing Generative Artificial Intelligence Tools and Applications [NOT-OD-25-081] – 3/28/2025
• Expired Early: Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences – 3/26/2025
• NIH Implementation of New Initiatives and Policies
• NIH Grants and Funding Information Status
• RESCINDED: NOT-OD-20-178 – Requirement for Trainee Diversity Report to be Submitted Electronically for Institutional Research Training, Career Development, and Research Education Awards Beginning in Early FY 2021 – Rescinded 3/17/2025
• NOT-OD-25-068, “Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates” – 2/7/2025
  • [Associated Press] Judge extends temporary block to huge cuts in National Institutes of Health research funding 2/21/2024
• PA-23-189, “Research Supplements to Promote Diversity in Health-Related Research” – Expired

NIJ – National Institute of Justice

• NIJ has cancelled all previously posted Notices of Funding Opportunity and associated webinars – 1/27/2025

NSF – National Science Foundation

• Frequently Asked Questions: Updates on NSF Priorities – updated 5/28/2025
• NSF 24-1: Proposal & Award Policies & Procedures Guide (PAPPG), effective for proposals submitted or due on or after May 20, 2024 – 5/21/2025
• Policy Notice: Implementation of Standard 15% Indirect Cost Rate – 5/2/2025
  • Defendants’ Notice in Response to the Court’s May 14, 2025 Order – 5/16/2025
• Temporary Restraining Order (directed to Federal grant-making agencies) – 1/31/2025
  • Award Cash Management Service (ACM$) has been restored – 2/2/2025
• Executive Order Implementation webpage – 1/28/2025

OPM – Office of Personnel Management

• Initial Guidance Regarding President Trump’s Executive Order Defending Women – 1/29/2025